Neuroblastoma Treatment and Clinical Trials
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Neuroblastoma treatment advancements through clinical trials
Over the years, many research studies (also known as clinical trials) have been conducted to understand the best ways to treat neuroblastoma. From these clinical trials, oncologists have established current standards for neuroblastoma treatment. Find more information on the current neuroblastoma treatment options.
A series of key clinical trials over this period improved treatment for each type of neuroblastoma:
High-risk neuroblastoma survival rates improve with treatment advancements
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Even though progress has been made, oncologists and researchers continue to develop new clinical trials with the hope of improving outcomes. As a result, many children with neuroblastoma are invited to enroll in a clinical trial as a part of their therapy.
Here is some information that may help when you are considering a clinical trial for your child.
Introduction to clinical trials
Clinical trials are research studies that test new ways to improve treatments in a group of people with a certain disease. In neuroblastoma, clinical trials often focus on new treatments to see if they are safer or more effective than what is currently available.
Clinical trials follow strict standards and are completely voluntary
- Clinical trials follow strict rules set by the Food and Drug Administration (FDA). These rules make sure that clinical trials are as safe as possible
- Participation in clinical trials is completely voluntary and you may choose to withdraw your child from a clinical trial at any time if you change your mind
Clinical trials are broken out by phases
The goal for a specific clinical trial will depend on the phase it's in.
- Early phase trials (phase 1 or 2) generally test whether new treatments are safe and effective
- Later phase trials (phase 3) generally test the standard treatment against a new alternative treatment. The goal for this type of trial is to see if the new alternative treatment helps to increase cure rates, decrease side effects, or limit late effects of treatment
- Children newly diagnosed with neuroblastoma are most commonly enrolled in phase 3 trials
Clinical trials may vary based on location
Different hospitals are associated with different research organizations, so some clinical trials may only be available at certain hospitals. Learn more about the different research groups in neuroblastoma.
The decision to explore clinical trials or choose the current standard treatment is one that should be made along with your child’s oncologist. Because every neuroblastoma diagnosis is unique, your child’s oncologist can help you find the treatment best tailored to meet the needs of your child.